Protective effect of ischemic postconditioning against hepatic ischemic reperfusion injury in rat liver

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Protective effect of ischemic postconditioning against hepatic ischemic reperfusion injury in rat liver

PURPOSE The efficiency of ischemic postconditioning (IPC) was evaluated in a rat model of ischemic liver. Concentration of survivin of liver tissue correlated with the degree of antiapoptosis, so survivin was estimated to evaluate the efficiency of IPC on ischemic reperfusion (IR) injury. METHODS Twenty-four healthy rats were divided to three groups (SHAM, IR, and IPC). Rats in the SHAM group...

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Protective effect of ischemic postconditioning against ischemia reperfusion-induced myocardium oxidative injury in IR rats.

Brief episodes of myocardial ischemia-reperfusion (IR) employed during reperfusion after a prolonged ischemic insult may attenuate the total ischemia-reperfusion injury. This phenomenon has been termed ischemic postconditioning. In the present study, we studied the possible effect of ischemic postconditioning on an ischemic reperfusion (IR)-induced myocardium oxidative injury in rat model. Resu...

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Protective Effect of Folic Acid against Apoptosis Induced by Ischemia/Reperfusion Injury in Rat Liver

       The anti-apoptotic gene bcl-2 is located in mitochondria, but it is uncertain whether its expression affects hepatocyte survival in ischemia/reperfusion (I/R) injury. This experiment was designed to evaluate the role of folic acid in expression of bcl-2 in I/R in rat liver. Eighteen Wister rats were divided into sham-operated controlgroup (C) (n=6), I/R group (...

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Ischemic preconditioning in hepatic ischemic-reperfusion injury

http://dx.doi.org/10.1016/j.fjs.2016. 1682-606X/Copyright a 2016, Taiwan S NC-ND license (http://creativecommo Abstract Background/Introduction: Ischemic preconditioning is a method in which brief periods of ischemia render tissues resistant to injury resulting from prolonged ischemia and reperfusion, so-called ischemiaereperfusion injury. Purpose: To elucidate the possible protective role of i...

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Protective Effect of Delayed Ischemic Postconditioning on Embolic Stroke Complications in Female Rat

Background & Aims: Ischemic postconditioning, conducted by a series of brief occlusion and release of the bilateral common carotid arteries, has neuroprotective properties in permanent or transient models of middle cerebral artery (MCA) occlusion but its delayed neuroprotective effects in the embolic model of stroke, especially in female rat, have not yet been reported and were investigated ...

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ژورنال

عنوان ژورنال: Annals of Surgical Treatment and Research

سال: 2015

ISSN: 2288-6575,2288-6796

DOI: 10.4174/astr.2015.88.5.241